Hello,
The get handle error is returned by the server to the client, so the server is unable to return a valid file handle for writing due to a lack of permission to either the directory.
Make sure your sftp user has write access to the directory E:\SFTP\Data\Customer\PeachCare\Outbout. If your user has list\read access they would be able to change directory, but would be unable to write to the directory.
You might also try a single file upload to see if there is a file that already exists on the server that is not allowing the file to be rewritten.